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Southern Meatloaf Recipe: Moist, Savory, and Full of Down-Home Flavor

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This Southern meatloaf is tender, flavorful, and topped with a sweet-savory ketchup glaze. A comforting, family-style dinner perfect for any night of the week.

Ingredients

Scale
  • 2 lbs ground beef (80/20)

  • 1 small onion, diced

  • ½ green bell pepper, diced

  • 1 cup crushed crackers (or breadcrumbs)

  • ⅓ cup milk

  • 2 eggs, lightly beaten

  • ½ cup ketchup (in mixture)

  • 2 tbsp Worcestershire sauce

  • 1 tsp yellow mustard (optional)

  • ½ cup ketchup (for glaze)

  • 2 tbsp brown sugar

  • 1 tsp apple cider vinegar

  • Salt and black pepper, to taste

  • 1 tbsp oil (for sautéing)

Instructions

  • Preheat oven to 350°F. Line a sheet pan or grease a loaf pan.

  • Sauté onion and bell pepper in oil until soft, about 5–7 minutes. Cool slightly.

  • In a large bowl, combine milk, crushed crackers, eggs, Worcestershire, ketchup, and optional mustard.

  • Add beef and sautéed veggies. Mix gently until combined.

  • Shape into loaf form or use a pan.

  • Mix ketchup, brown sugar, and vinegar. Spread over top.

  • Bake for 55–65 minutes, until internal temp reaches 160°F.

  • Rest for 10 minutes before slicing.

Notes

  • Substitute ground turkey for a leaner version.

  • Use BBQ sauce for a smoky glaze.

  • Leftovers make excellent sandwiches.